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Dementia Matters

Wisconsin Alzheimer‘s Disease Research Center

Available on

Dementia Matters is a podcast about Alzheimer‘s disease and other causes of dementia. Host Dr. Nathaniel Chin interviews leading scientists and caregiving experts to bring listeners the latest in Alzheimer’s disease news, research and caregiver resources. Brought to you by the Wisconsin Alzheimer’s ...

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    The Fundamentals of Neuropsychology: Breaking Down Cognition, Memory and More

    <p>The brain is the most complex part of the human body, controlling thought, memory, emotion, motor skills, sensory input and all the processes that regulate our bodies. How ...

    Long COVID and Its Effect on Cognition

    <p>Since the COVID-19 pandemic was declared by the World Health Organization (WHO) in 2020, there have been many concerns about how cases of COVID-19 and Long COVID or Post-CO...

    Listen Up! The Connections Between Hearing Loss, Hearing Interventions and Cognitive Decline

    <p>Hearing loss affects roughly <a href='https://www.ncoa.org/adviser/hearing-aids/hearing-loss-statistics/'>15.5% of Americans 20 years and older</a>. While the majority of t...

    From Caregiver to Research Participant: How One Woman’s Experience as a Dementia Caregiver Drew Her to Alzheimer’s Research

    <p>Caring for a loved one with cognitive decline can be challenging. While it is a labor of love, burnout is all but inevitable. In this episode kicking off our Voices of Rese...

    Looking at Lecanemab’s Eligibility Guidelines and Prescription Process

    <p>In the past few years, new therapies shown to slow the progression of Alzheimer's disease in people in the early stages of the disease have been making their way through th...

    Do Non-Medicinal Interventions Reduce Dementia Risk? Studies are Inconclusive, Here’s Why

    <p>In 2017, the National Academies of Sciences, Engineering, and Medicine published a report showing promising but inconclusive evidence suggesting that interventions like cog...

    The Road to Hope: Philanthropy’s Impact on Alzheimer’s Research

    <p>In this year-end episode of <em>Dementia Matters</em>, we explore the vital role of philanthropy in advancing Alzheimer's disease research and care. Mr. Dave Adam serves on...

    Could Green Tea Hold the Key to New Alzheimer’s Treatments?

    <p>Dr. Paul Seidler joins the podcast to discuss his recent study looking at the connection between molecules in green tea and tau proteins. He also discusses the impact those...

    The Impact of Social Isolation on Dementia Risk in Older Adults

    <p>In May 2023, the U.S. Surgeon General, Dr. Vivek Murthy, released an advisory calling attention to the public health crisis of loneliness and social isolation in the U.S. W...

    Memories and Milestones: Celebrating Six Years of ‘Dementia Matters’

    <p>Six years following the start of <em>Dementia Matters</em> in October 2017, the podcast team turns the tables on our host, Dr. Nathaniel Chin. Producers Amy Lambright Murph...

    Crosswords or Computers: Which is Better for Cognitive Engagement?

    <p>Cognitive engagement is vital to keeping your brain healthy since it can slow shrinkage and induce neuroplasticity. While modern technology offers many new tools and games ...

    RAISE(ing) Support for Caregivers: State and National Resources for Family Care Partners

    <p>Dementia caregiving is a multifaceted domain, deeply influenced by research, strategy and personal experiences. How are these elements shaping the current and future landsc...

    Mental Health and Memory: The Connections between Chronic Mental Illness and Dementia

    <p>Like cognition, mental health is a key component of the brain — and overall — health. In what ways can mental health and chronic mental illness impact a person’s cognition ...

    Highlights from the 2023 Alzheimer’s Association International Conference

    <p>The 2023 Alzheimer's Association International Conference (AAIC) in Amsterdam brought together the world's leading scientists, clinical researchers, early career investigat...

    A Fair Fight Against Alzheimer’s: The Need for Equity in Dementia Research and Care

    <p>How can we ensure that all communities are represented in Alzheimer’s and related dementias research and have access to the latest treatments and interventions? Dr. Carl Hi...

    Agitation and Alzheimer’s: Strategies for Managing Behavioral and Psychological Symptoms of Dementia

    <p>Many people living with dementia experience behavioral symptoms alongside changes in their cognition. What can care partners and healthcare providers do to manage these beh...

    Promises to Practice: Creating Sustainable Community Partnerships to Support Alzheimer’s Research

    <p>Gina Green-Harris joins the podcast to discuss the importance of collaborating with communities in Alzheimer’s research. Sharing her experience as a researcher with the Wis...

    Study Shows APOE Gene Affects Hispanic Populations’ Risk of Cognitive Decline Differently to Non-Hispanic Populations

    <p>The APOE gene is recognized as a significant genetic risk factor for cognitive decline, with different alleles, like APOE e2, being seen as protective against decline and o...

    Putting Lecanemab into Practice: A Clinician’s Perspective on the New Alzheimer’s Treatment

    <p>On July 6, 2023, the U.S. Food and Drug Administration (FDA) granted full approval for the Alzheimer’s disease drug Leqembi (lecanemab-irmb), the first medicine shown to de...

    Deciding to Donate: Barriers and Benefits of Brain Donations for Diverse Populations

    <p>Dr. Crystal Glover, health equity in aging researcher at Rush Alzheimer’s Disease Center, joins the podcast to discuss the importance of increasing brain donations and tiss...

    Lecanemab, Clinical Trials, and the Importance of Clinical Meaningfulness

    <p>On June 9, 2023, the Food and Drug Administration’s (FDA) advisory committee unanimously voted to approve lecanemab, moving the treatment one step closer to full FDA approv...

    Understanding the Social Determinants of Health and Disparities in Alzheimer’s Research

    <p>Dr. Lisa Barnes joins the podcast to discuss her research focusing on how social determinants of health, specifically racial differences, affect chronic diseases of aging.S...

    Take Care of Your MIND: Reviewing the MIND Diet for Healthy Brain Aging

    <p>To mark National Mediterranean Diet Month, Dr. Nathaniel Chin discusses a recent National Institute on Aging-funded study that suggests the MIND and Mediterranean diets — b...

    The National Strategy for Diversifying Alzheimer’s Research

    <p>Dr. Sarah Biber, the program director for the National Alzheimer’s Coordinating Center (NACC), joins the podcast to discuss efforts to increase representation and equitable...

    The Future of Neuroscience: Early-Career Researchers Named ’One to Watch’ by the Alzheimer’s Association

    <p>Recorded live from the Wisconsin ADRC’s Alzheimer’s Disease & Related Dementias Research Day, Dr. Nathaniel Chin discusses the importance of mentorship and the future of ne...

    Studies Look at Generational Differences and Associations between Cognition, Sensory Changes and Blood Biomarkers

    <p>Dr. Natascha Merten joins the podcast to discuss her study focused on trends in cognitive function across generations. Merten also explains her research on the associations...

    Disclosing Alzheimer’s Disease Biomarker Results in Diverse Populations

    <p>Dr. Annalise Rahman-Filipiak joins the podcast to discuss her research focused on disclosing neuroimaging biomarkers across diverse populations. She addresses why some peop...

    Difficult but Beneficial Conversations about End-of-Life Care

    <p>For families and dementia care partners, palliative care can help improve the quality of life for their loved ones and themselves by addressing physical and emotional needs...

    Caregiving While Black: Dementia Care for Different Racial and Ethnic Groups

    <p>When seeking medical information and treatment, different racial and ethnic groups may require specially tailored information to relate to, understand and apply to their ow...

    Our Evolving Understanding of Mild Cognitive Impairment

    <p>Mild cognitive impairment (MCI) is an emerging term in the field of Alzheimer’s disease and related dementias, characterized as the stage between the expected decline in me...

    A Closer Look at the Lecanemab Clinical Trials

    <p>In a special episode of Dementia Matters, Drs. Cynthia Carlsson and Sterling Johnson join the podcast to discuss what they know from lecanemab’s clinical trials following t...

    Therapeutic Fibbing: Mastering the Art of Communicating with a Loved One with Dementia

    <p>Former Governor of Wisconsin, Martin Schreiber, returns to <em>Dementia Matters</em> to discuss different methods for communicating with a loved one with Alzheimer’s diseas...

    The Future of the Alzheimer’s Association: Interview with Dr. Joanne Pike and Harry Johns

    <p>In October 2022, the Alzheimer's Association named Dr. Joanne Pike, the current president of the Association, as the next CEO, succeeding Harry Johns who has served as CEO ...

    Introducing Lecanemab, the Latest Alzheimer’s Disease Drug to Receive FDA Accelerated Approval

    <p><a href='https://www.adrc.wisc.edu/nathaniel-chin-md'>Host Nathaniel Chin, MD,</a> gives an overview of the new Alzheimer’s treatment Leqembi (lecanemab), and highlights re...

    Healthy Habits for the New Year and Modifiable Risk Factors for Alzheimer’s Disease

    <p><a href='https://www.adrc.wisc.edu/nathaniel-chin-md'>Host Nathaniel Chin, MD,</a> starts the new year by discussing modifiable risk factors for Alzheimer’s disease, commen...

    Bioenergetics: How Mitochondria Affects Alzheimer’s Disease and Aging

    <p>It’s generally known that mitochondria are the powerhouse of cells, but did you know they can play a significant role in aging processes? Through the field of bioenergetics...

    Looking Toward the Future: How Preclinical Alzheimer’s Disease Biomarker Disclosures Impact Society

    <p>The field of biomarkers is advancing quickly, allowing preclinical Alzheimer’s disease to be identified earlier and earlier in a person’s life. As individuals learn they ar...

    Mixed Dementia, Explained

    <p>Though brain and cognitive changes are typically diagnosed as one form of dementia, recent studies have shown that mixed dementia is more common than previously thought. Mi...

    The Case for Disclosing Biomarker Results to Alzheimer’s Research Participants

    <p>Though several validated biomarkers are studied and used in Alzheimer’s disease research, most research participants don’t have the opportunity to learn their biomarker res...

    Promoting Open Science and Community Engagement with the National Institute on Aging

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 6</p> <p>Concluding our special series on the 2022 Spring ADRC Meeting...

    Moving into the Digital Era of Alzheimer’s Disease Research

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 5</p> <p>Whether it be due to new research findings, innovative approa...

    National Efforts to Standardize Brain Scan Data for More Accurate Alzheimer’s Risk Predictions

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 4</p> <p>Brain imaging is a key tool in Alzheimer’s disease research a...

    Protecting Participant Privacy and Making Predictions Using Alzheimer’s Data

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 3</p> <p>With big data comes big responsibility. Dr. Sean Mooney joins...

    The Future of Sharing and Accessing Alzheimer’s Disease Data

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 2</p> <p>Dr. Sarah Biber, the program director for NACC, joins the pod...

    Introducing the National Alzheimer’s Coordinating Center

    <p>Dementia Matters Special Series: The National Strategy for Alzheimer's Disease Data and Research Part 1:</p> <p>Kicking off our six-episode series on the National Alzheimer...

    Study Shows APOE e4 Not Associated with Alzheimer’s Disease in American Indian Populations

    <p>Researchers typically recognize the APOE e4 gene as a significant genetic risk factor for cognitive decline and dementia. However, a new study has found that the allele is ...

    Improving Registries and Representation in Alzheimer’s Disease Research

    <p>Research participants are recruited through a variety of practices. One of the most popular tools are registries, but how can registries affect diversity and representation...

    Highlights from the 2022 Alzheimer’s Association International Conference

    <p>AAIC Special Series Part 8:</p> <p>Closing out our special series spotlighting the 2022 Alzheimer’s Association International Conference, Dr. Percy Griffin joins the podcas...

    COVID-19 and Its Effects on the Brain

    <p>AAIC Special Series Part 7:</p> <p>Recent studies have shown that 1 in 5 U.S. adults who were diagnosed with COVID-19 now deal with Long COVID, a condition where individual...

    Apathy and Alzheimer’s Disease: Plenary Preview with Dr. Krista Lanctôt

    <p>AAIC Special Series Part 6:</p> <p>Dr. Krista Lanctôt joins the podcast to discuss apathy, how it develops in people with Alzheimer’s disease, and her upcoming AAIC 2022 pl...

    Scientific Importance of Diversity in Alzheimer’s Disease Research

    <p>AAIC Special Series Part 5:</p> <p>Bringing together scientists, clinicians, and research participants from all over the world, AAIC 2022 showcases the work and experiences...

    Delirium and Dementia: Plenary Preview with Dr. Sharon Inouye

    <p>AAIC Special Series Part 4:</p> <p>Research into delirium, a condition where older adults experience acute confusional states during hospitalizations, and its connections t...

    Non-Pharmacological Care for People with MCI and Dementia: Plenary Preview with Dr. Linda Lam

    <p>AAIC Special Series Part 3:</p> <p>Mild cognitive impairment (MCI) is an early stage of memory loss and cognitive impairment that can develop into dementia. While physician...

    Opening Doors to Research Participants: Making Scientific Conferences Accessible to the Public

    <p>AAIC Special Series Part 2:</p> <p>Attending scientific conferences is usually a major commitment, often requiring attendees to travel, pay attendance fees, and take time o...

    The World’s Largest Forum for Alzheimer’s Research: Introducing the AAIC 2022 Special Series

    <p>AAIC Special Series Part 1:</p> <p>To kick off our month-long special series previewing the 2022 Alzheimer’s Association International Conference, or AAIC, we’ve invited  C...

    Study Shows Do-Not-Resuscitate Orders Can Lead to Worse Care, Increase Death Rates

    <p>A do-not-resuscitate, or DNR, order is used to indicate when a patient chooses to forgo resuscitation, however recent analysis shows that multiple studies have connected th...

    ‘Finding the Right Words’: Author Interview with Cindy Weinstein and Bruce Miller

    <p>American literature professor and author Cindy Weinstein and behavioral neurologist Bruce Miller join the podcast to discuss their latest book, "Finding the Right Words: A ...

    Alcohol and the Brain: One Drink a Day Associated with Brain Shrinkage

    <p>There are many conflicting studies on how alcohol consumption can impact a person’s health, with some studies suggesting light drinking can protect against coronary heart d...

    Women’s Health Month: Women and Alzheimer’s Disease

    <p>In honor of Women’s Health Month, Dr. Jessica Caldwell joins the podcast to discuss sex differences in aging and Alzheimer’s disease. She explains some of the ways women ex...

    Disaggregating Racial Data: How Studying Ethnic Subgroups Can Improve Research

    <p>A graduate student from the University of Wisconsin–Madison is pushing for the disaggregation of data in research to better understand how individuals from different ethnic...

    Incorporating Cultural Knowledge: Improving Alzheimer’s Disease Research for Veterans and Native Americans

    <p>Dr. Cynthia Carlsson and Daniel A. King join the podcast to discuss some of the unique ways that Alzheimer’s disease affects Veterans and Native Americans. Their work at th...

    Update on Blood Tests for Alzheimer’s Disease

    <p>Research in the field of fluid biomarkers is leading to new developments in Alzheimer’s disease identification, including new tests that can predict Alzheimer’s based on bi...

    Harnessing the Power of Autophagy to Treat Alzheimer’s Disease

    <p>The Puglielli lab at the University of Wisconsin School of Medicine and Public Health has found a way to manipulate autophagy — a process where cells clean out damaged mate...

    Go with the (4D) Flow: Neuroimaging Technology Used to Study Overlap of Cerebrovascular Disease and Alzheimer’s

    <p>A recent study from Alzheimer’s disease researchers at the University of Wisconsin–Madison used neuroimaging technology called 4D Flow MRI to study the relationship between...

    Breaking Down Medicare’s Proposed Decision on Aducanumab and Monoclonal Antibody Treatments

    <p>On January 11, the Centers for Medicare and Medicaid Services (CMS) announced its much-anticipated coverage proposal for monoclonal antibody treatments that target amyloid ...

    Nasal Vaccine for Alzheimer’s Disease Enters Clinical Trial

    <p>In November 2021, Brigham and Women’s Hospital in Boston launched the first human trial of a nasal vaccine for Alzheimer’s disease. Nearly 20 years of research went into de...

    ‘American Dementia’: Author Interview with Dr. Daniel George and Dr. Peter Whitehouse

    <p>Medical anthropologist and professor of humanities and public health sciences Daniel George, PhD, and professor of neurology and medicine Peter Whitehouse, MD, PhD, join th...

    New Research Shifts Thinking on Metabolism and Aging

    <p>There are many common beliefs about metabolism. Perhaps you’ve heard that a person’s metabolism slows around middle age, or that a woman’s metabolism is slower than a man’s...

    Aging Behind the Wheel: How Driving Behavior Can Identify Preclinical Alzheimer’s Disease

    <p>Dementia impacts a person’s ability to complete day-to-day activities like familiar tasks at work or at home. What if we could identify these changes in everyday behaviors ...

    Global Challenges in Dementia Diagnosis: A Deep Dive into ADI’s World Alzheimer’s Report 2021

    <p>Alzheimer’s Disease International’s World Alzheimer’s Report 2021 recently found that 75% of people with dementia are undiagnosed, equating to 41 million people across the ...

    Accessibility and Community: Bringing Alzheimer’s and Dementia Resources to the Latinx Community

    <p>UsAgainstAlzheimer’s newly-released tool, BrainGuide, may seem like a simple questionnaire, but the project highlights a growing movement to make Alzheimer’s disease resear...

    You Are What You Eat: Study of Diet and Brain Health Shows Cognitive Benefits from Cheese, Wine and Lamb

    <p>A recent study of nearly 1,800 participants from the UK Biobank found that three dietary elements — cheese, wine, and lamb — may improve long-term cognitive outcomes in agi...

    AARP Study Shows Stigma Surrounding Dementia among Healthcare Professionals and General Public

    <p>With the numerous efforts currently focused on educating the public about dementia, from clinical programs to research to podcasts (like this one), how much is stigma surro...

    Caregivers, Care Partners and People with Dementia: Brainstorming New Interventions for Dementia Care

    <p>When talking about dementia caregiving, researchers are often working toward new treatments and strategies for supporting people with Alzheimer’s disease and dementia. But ...

    Tackling Stigma and Alzheimer’s Disease within the AAPI Community

    <p>Vince Tien and Dr. Dung Trinh join the podcast to discuss the many ways Alzheimer’s disease affects the Asian Americans and Pacific Islanders (AAPI) community. Vince Tien a...

    Creative Care: The Power of Imagination in Dementia Caregiving

    <p>What would happen if caregiving strategies were inspired by wonder rather than memory? That’s what Dr. Anne Basting, founder and president of the nonprofit TimeSlips, asked...

    Better Now than Never: Quit Smoking to Reduce Your Risk for Alzheimer’s Disease

    <p>Researchers have produced many studies on how smoking affects parts of the body, such as the lungs or heart, but what about the brain? In today’s podcast, Adrienne Johnson,...

    Dentistry and Dementia: The Importance of Caring for Oral Health

    <p>Elisa Ghezzi, DDS, PhD, joins the podcast to discuss the importance of maintaining oral health throughout one’s life, and especially as one grows older. Discussing the effe...

    Vote for Dementia Matters in the 2021 Podcast Awards!

    <p>Dementia Matters has entered into the 2021 People's Choice Podcast Awards! If you enjoy our show and want to support us, register and vote before July 31st at www.podcastaw...

    From Studying to Living with Alzheimer‘s Disease: A Conversation with Dr. Daniel Gibbs

    <p>Neurologist and author Daniel Gibbs, PhD, joins the podcast to discuss his recent book, “A Tattoo on My Brain,” which details his journey from treating Alzheimer’s disease ...

    How Close Are We to Curing Alzheimer’s Disease?

    <p>For our 100th episode of <em>Dementia Matters</em>, Nina Silverberg, PhD, director of the Alzheimer's Disease Research Centers (ADRC) Program at the National Institute on A...

    How to Shape Your Brain Health and Reduce Your Risk for Alzheimer’s Disease

    <p>Neuropsychologist and author Michelle Braun, PhD, joins the podcast to talk about lifestyle changes that can support brain health. “We have the ability to make our brain yo...

    Study Finds Air Pollution a Risk Factor for Alzheimer’s Disease

    <p>Researchers at the University of California, San Francisco found that among older adults with cognitive impairment, the greater the air pollution in their neighborhood, the...

    Managing Inappropriate Sexual Behavior in Alzheimer’s Disease

    <p>Inappropriate sexual behavior is a common yet rarely discussed symptom in individuals with dementia. Author Elizabeth Marcus writes about her personal experience with her f...

    Being Patient Translates Alzheimer’s Disease Science for the General Public

    <p><em>Being Patient</em> is an online news source dedicated to providing research news, caregiver information and resources related to Alzheimer's disease. <em>Being Patient<...

    How Society Can Improve Care for People with Alzheimer’s Disease and Related Dementias

    <p>Dr. Jason Karlawish discusses society’s role in addressing care for individuals with memory loss, as well as current stigmas around Alzheimer’s disease, Wealthcare, and his...

    The Healthcare System’s Role in Alzheimer’s Disease

    <p>Dr. Jason Karlawish joins the podcast for the third installment in our series on his new book, "<em>The Problem of Alzheimer's: How Science, Culture, and Politics Turned a ...

    How Culture, Society and Politics Shaped Alzheimer’s Disease Research

    <p>Dr. Jason Karlawish returns to the podcast to continue our discussion on his new book, The Problem of Alzheimer's: How Science, Culture, and Politics Turned a Rare Disease ...

    The Past, Present and Future of Alzheimer’s Disease Research

    <p>Physician and author Dr. Jason Karlawish joins the podcast for the first installment of a four-part series centered around his new book, <em>The Problem of Alzheimer's: How...

    Research Suggests Financial Problems an Early Sign of Alzheimer’s Disease

    <p>In a recent study, health economist Lauren Nicholas, PhD, found older adults who go on to be diagnosed with dementia are more likely to miss payments on bills as early as s...

    The Powerful Benefits of Music on Memory Loss

    <p>Growing research has shown that music can have a profound impact on individuals with memory loss. Right to Music is an organization dedicated to promoting use of personal m...

    Emergency Care Tips for People with Dementia

    <p>Visiting the emergency department can be a challenging experience for individuals with memory loss and their caregivers. Dr. Manish Shah joins the podcast to discuss the di...

    Safely Disclosing Amyloid Results with Alzheimer’s Disease Research Participants

    <p>Dr. Lindsay Clark’s new study will evaluate the psychological consequences of disclosing amyloid test results to cognitively unimpaired adults. Dr. Clark joins the podcast ...

    Poetry and Memory: A Poem by Dr. Fabu Carter

    <p>In this special holiday bonus episode, we are joined by poet laureate, writer, and senior outreach specialist, Dr. Fabu Carter, to discuss the impact of poetry on memory lo...

    Update on Blood Tests for Predicting Alzheimer’s Disease

    <p class="p1">Recent developments have introduced a blood-based test that could predict Alzheimer’s disease, with more of these tests currently in development. Dr. Sterling Jo...

    Vitamin Deficiency and Its Impact on Brain Health

    <p>A study from the University of Wisconsin found 40% of geriatric memory patients were deficient in at least one vitamin linked to brain health. Vitamins tested in this study...

    Benefits of an Early Alzheimer’s Disease Diagnosis

    <p>For individuals concerned with memory loss, the first few steps for screening and diagnosis can be the most intimidating. Dr. Cynthia Carlsson discusses recent progress in ...

    Defining Mild Cognitive Impairment with Dr. Chin

    <p>On October 27th, the NBC drama series <em>This Is Us</em> will return for a fifth season. An integral storyline in the show is the diagnosis of one of the main characters, ...

    Intermittent Fasting and Its Effects on the Brain

    <p>As intermittent fasting has risen in popularity over the last decade, researchers have been exploring its long-term effects on physical health. Dr. Mark Mattson joins to di...

    Research Update: Aerobic Exercise and Brain Health

    <p>Aerobic exercise is often a recommendation for maintaining cognitive well-being, however its true connections to brain health are still being investigated to learn its effe...