ProfessorMichaelLevin

Faculty of Medicine, Department of Infectious Disease

Chair in Paediatrics & International Child Health

Contact

Location

233Medical SchoolSt Mary's Campus

Summary

Michael Levin MBE PhD FRCPCH FMedSci is Professor of Paediatrics and International Child Health at Imperial College London. He works as a paediatric infectious diseases consultant and has led research focused on the diagnosis and treatment of a range of childhood infections including meningococcal disease, tuberculosis, bacterial sepsis and Kawasaki disease. He led the EU funded PERFORM study investigating the application of RNA transcriptomics to improve diagnosis of childhood infection. He also led the NIH funded study Validation of Biomarkers of Pediatric TB and further development for use in diagnosis of childhood TB.

In 2020 he was awarded €22.5 million EU funding to develop a rapid test for serious illnesses – the DIAMONDS project (Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis)

Professor Levin received an MBE for his services to infectious disease, critical care and research in paediatrics in the Queen’s New Year’s honour list in 2017.

Selected Publications

Journal Articles

Martinón-Torres F, Salas A, Rivero-Calle I, et al.Martinón-Torres F, Salas A, Rivero-Calle I, Cebey-López M, Pardo-Seco J, Herberg JA, Boeddha NP, Klobassa DS, Secka F, Paulus S, de Groot R, Schlapbach LJ, Driessen GJ, Anderson ST, Emonts M, Zenz W, Carrol ED, Van der Flier M, Levin M, Levin M, Coin L, Gormley S, Hamilton S, Herberg J, Hourmat B, Hoggart C, Kaforou M, Sancho-Shimizu V, Wright V, Abdulla A, Agapow P, Bartlett M, Bellos E, Eleftherohorinou H, Galassini R, Inwald D, Mashbat M, Menikou S, Mustafa S, Nadel S, Rahman R, Thakker C, Bokhandi S, Power S, Barham H, Pathan N, Ridout J, White D, Thurston S, Faust S, Patel S, McCorkell J, Davies P, Crate L, Navarra H, Carter S, Ramaiah R, Patel R, Tuffrey C, Gribbin A, McCready S, Peters M, Hardy K, Standing F, O'Neill L, Abelake E, Deep A, Nsirim E, Pollard A, Willis L, Young Z, Royad C, White S, Fortune PM, Hudnott P, Martinón-Torres F, Salas Ellacuriaga A, Álvez González F, Barral-Arca R, Cebey-López M, Curras-Tuala MJ, García N, García Vicente L, Gómez-Carballa A, Gómez Rial J, Grela Beiroa A, Justicia Grande A, Leboráns Iglesias P, Martínez Santos AE, Martinón-Torres N, Martinón Sánchez JM, Morillo Gutiérrez B close, 2018, Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study, Lancet Child and Adolescent Health, Vol:2, ISSN:2352-4642, Pages:404-414

Boeddha NP, Schlapbach LJ, Driessen GJ, et al.Boeddha NP, Schlapbach LJ, Driessen GJ, Herberg JA, Rivero-Calle I, Cebey-López M, Klobassa DS, Philipsen R, de Groot R, Inwald DP, Nadel S, Paulus S, Pinnock E, Secka F, Anderson ST, Agbeko RS, Berger C, Fink CG, Carrol ED, Zenz W, Levin M, van der Flier M, Martinón-Torres F, Hazelzet JA, Emonts M, EUCLIDS consortium close, 2018, Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS), Critical Care, Vol:22, ISSN:1364-8535

von Both U, Berk M, Agapow P-M, et al.von Both U, Berk M, Agapow P-M, Wright J, Git A, Hamilton MS, Goldgof G, Siddiqui N, Bellos E, Wright V, Coin L, Newton S, Levin M close, 2018, Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival, Scientific Reports, Vol:8, ISSN:2045-2322

Kaforou M, Herberg JA, Wright VJ, et al.Kaforou M, Herberg JA, Wright VJ, Coin LJM, Levin M close, 2017, Diagnosis of bacterial infection using a 2-transcript host RNA signature in febrile infants 60 days or younger, JAMA - Journal of the American Medical Association, Vol:317, ISSN:0098-7484, Pages:1577-1578

Herberg JA, Kaforou M, Wright VJ, et al.Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M close, 2016, Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children, Journal of the American Medical Association, Vol:316, ISSN:0002-9955, Pages:835-845

Kaforou M, Wright VJ, Levin M, 2014, Host RNA signatures for diagnostics: An example from paediatric tuberculosis in Africa, Journal of Infection, Vol:69, ISSN:0163-4453, Pages:S28-S31

Anderson ST, Kaforou M, Brent AJ, et al.Anderson ST, Kaforou M, Brent AJ, Wright VJ, Banwell CM, Chagaluka G, Crampin AC, Dockrell HM, French N, Hamilton MS, Hibberd ML, Kern F, Langford PR, Ling L, Mlotha R, Ottenhoff THM, Pienaar S, Pillay V, Scott JAG, Twahir H, Wilkinson RJ, Coin LJ, Heyderman RS, Levin M, Eley B close, 2014, Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa, New England Journal of Medicine, Vol:370, ISSN:1533-4406, Pages:1712-1723

Eleftherohorinou H, Hoggart CJ, Wright VJ, et al.Eleftherohorinou H, Hoggart CJ, Wright VJ, Levin M, LJM C close, 2011, Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways, Human Molecular Genetics, Vol:20, Pages:3494-3506

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